Oligosaccharides / Glycans

  • Core structures
  • Blood groups & Lewis antigens
  • Lactose based O-glycans
  • Ganglioside oligosaccharides
  • Globo series
  • Galα1-3Gal series
  • Sialylated oligosaccharides
  • Glucuronylated oligosaccharides

Natural polysaccharides & derived-oligosaccharides

  • Glucans: xyloglucans, cellodextrin, maltodextrin, lichenan / isolichenan, scleroglucan, pustulan
  • Xanthan
  • Chitin & chitosan: oligochitin
  • Ulvan
  • Fucan
  • Mannans: mannan, xylomannan, galactomannan, glucomannan, galactoglucomannan
  • Alginates: manuronic and guluronic oligosaccharides
  • Galacturonan & apiogalaturonan
  • Fructan

Analytical references

  • Highly purity oligosaccharides (including several HMO) characterized with
  • Quantitative 1H-NMR (based on a qualified internal standard) and High performance chromatographic techniques (HPLC and/or HPAEC-PAD) for purity determination and impurities detection
  • Structure validation by 13-NMR & Mass spectrometry
  • Determination of residual water content after freeze-drying by Karl-Fisher titration

Glycoconjugates

  • Neoglycoproteins
  • BSA/OVA/KLH-conjugated oligosaccharides
  • Affinity chromatography columns
  • Biotinylated oligosaccharides
  • Fluorescent labeled oligosaccharides

Functionalized oligosaccharides (spacer arm & terminal function)

-O-(CH2)3-NH2
-O-EG2-NH2
-O-EG3-NH2
-O-CH2-CΞCH
-O-CH2-CH=CH2
-O-CH2-CO-CH3
-O-(CH2)3-CH=CH2
-O-(CH2)3-S-(CH2)2-NH2
-O-CH2-(1,4-Tz)-(CH2)6-NH2
-O-CH2-(1,4-Tz)-(CH2)2-EG3-NH2
-O-CH2-(1,4-Tz)-(CH2)2-EG7-NH2
-O-EG2-Cl
-O-EG3-N3
-O-CH2-(1,4-Tz)-(CH2)2-EG3-NH-Bt
-O-CH2-(1,4-Tz)-(CH2)2-EG3-NH-DestBt
-O-(CH2)3-NH-CS-NH-Fluorescein
-NAc-CH2-CH=CH2
-NAc-CH2-CΞCH
-NAc-CH2-(1,4-Tz)-(CH2)2-EG3-NH2
-NAc-CH2-(1,4-Tz)-(CH2)2-EG7-NH2
-NAc-CH2-(1,4-Tz)-(CH2)6-NH2
-NAc-CH2-(1,4-Tz)-(CH2)2-EG3-NH-Bt
-NAc-CH2-(1,4-Tz)-(CH2)2-EG3-NH-DestBt

Lectins

  • Bacteria lectins : LecA & LecB from P. aeruginosa, RSL from R. solanacearum, BC2LA & BC2LC-Nt from B. cenocepacia
  • Human lectins : DC-SIGN, Langerin

13C/15N labeled oligosaccharides